Webinar

Understand and Mitigate Interface-Induced Risks in Biopharmaceutical Development with QSense QCM-D

Join this webinar to learn how QSense QCM-D can be used to investigate interface-related risks in biopharmaceutical development, from early developability through formulation and fill–finish.

Surface-induced processes such as adsorption, unfolding and aggregation at solid–liquid interfaces are increasingly recognized as potential contributors to subvisible particles (SVPs), long-term interfacial changes and material compatibility issues.

In this session, Fredrik Pettersson, Senior Application Scientist at Biolin Scientific, will show how nanoscale adsorption measurements using QSense QCM-D can be used to establish mechanistic links to macroscopic outcomes such as SVP formation, aggregation, and interfacial stability overtime.

 

 

Webinar details

  • Date
    March 10, 09:00 CET
  • Length
    1 hour
  • Presentation by
    Dr. Fredrik Pettersson
  • Technologies
    QCM-D
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anti-biofouling polymers

In this webinar:

The webinar presents four recent case studies from publications where QSense QCM-D was applied to development-relevant questions across molecule selection, formulation, container/closure compatibility, fill–finish equipment materials, and long-term interfacial stability. Together, the examples illustrate how QSense can complement traditional stress testing and bulk assays, and support more informed discussion around molecule, excipient and material choices.

The webinar may be of particular interest to professionals involved in biopharmaceutical development who are interested in incorporating interface-focused, mechanistic insights into their work.

Agenda

Overview: Interface-induced instabilities and why surfaces matter in biopharma development
QSense QCM-D as a mechanistic tool for antibody–surface interaction and stability assessment
Case examples from recent publications:
  • Paper 1:Interface-mediated SVP risk and mAb selection
  • Paper 2: Surfactant and container/closure compatibility (glass, polymers, silicone oil systems)
  • Paper 3: Metals, pumps and fill–finish: adsorption on steels, ceramics and coatings
  • Paper 4: Antibody conformation and long-term interfacial stability on glass/oxide vs stainless steel
Fredrikrunt

Presentation by Fredrik Pettersson

Fredrik Pettersson is a Senior Application Scientist at Biolin Scientific, specializing in QSense QCM-D and surface and interface analysis. With an M.Sc. in Biophysical Engineering, he has built broad technical expertise through work in e.g.  drug screening and surface science. He uses advanced surface measurements to solve real-world interfacial challenges, translating complex data into clear, useful insights that help users understand system behavior and make better decisions in both fundamental studies and applied work on processes, materials, and products.

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